fentanyl transdermal and pentobarbital each boost sedation. Stay clear of or Use Alternate Drug. Limit use to clients for whom different procedure possibilities are inadequate
pentobarbital will lessen the extent or result of mifepristone by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch. CYP3A4 inducers haven't been researched, coadministration not encouraged by manufacturer
Soon after halting a CYP3A4 inducer, as the results from the inducer drop, the fentanyl plasma concentration will raise which could raise or extend both of those the therapeutic and adverse results.
pentobarbital will decrease the level or outcome of cortisone by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.
pentobarbital will lessen the extent or influence of celecoxib by impacting hepatic enzyme CYP2C9/ten metabolism. Slight/Importance Not known.
pentobarbital will reduce the level or outcome of triazolam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.
pentobarbital will minimize the extent or influence of docetaxel by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Importance Unidentified.
pentobarbital will lessen the level or outcome of roflumilast by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Coadministration not advisable; powerful cytochrome P450 enzyme inducers decrease systemic publicity to roflumilast and will lessen the therapeutic performance
pentobarbital will reduce the extent or effect of montelukast by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Importance Mysterious.
pentobarbital and daridorexant equally maximize sedation. Modify Therapy/Monitor Intently. Coadministration raises risk of CNS depression, which can result in additive impairment of psychomotor performance and bring about daytime impairment.
pentobarbital will lessen the extent or result of parecoxib by influencing hepatic enzyme CYP2C9/10 metabolism. Use Warning/Monitor.
pentobarbital will increase click here toxicity of methoxyflurane by growing metabolism. Contraindicated. Increased metabolism of methoxyflurane to nephrotoxic compounds.
pentobarbital will reduce the extent or outcome of estradiol vaginal by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.
pentobarbital will reduce the level or impact of nicardipine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.